N-COUMARINYL-L-PROLINE, A NOVEL CHIRAL DERIVATIZING AGENT FOR ^1H NMR DETERMINATION OF ENANTIOMERIC PURITIES OF ALCOHOLS AND AMINES

Abstract

N-(Coumarin-4-yl)-L-proline[CPRO-1], readily prepared from commercially available Cbz-L-proline and 4-hydroxycoumarin, was proved to be an efficient and useful chiral derivatizing agent by ^1H NMR inspection of the resulting diastereomeric esters and amides.

Journal

Chemical & pharmaceutical bulletin   [List of Volumes]

Chemical & pharmaceutical bulletin 43(2), 344-346, 1995-02-15  [Table of Contents]

The Pharmaceutical Society of Japan

References:  11

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Codes

  • NII Article ID (NAID) :
    110003631473
  • NII NACSIS-CAT ID (NCID) :
    AA00602100
  • Text Lang :
    ENG
  • Article Type :
    SHO
  • ISSN :
    00092363
  • Databases :
    CJP  NII-ELS 

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