The properties of water of crystallization of sodium prasterone sulfate.

• 中川 寛

• 高橋 嘉輝

• 藤本 喜昭

• 前田 四郎

• 杉本 功

抄録

The properties of water of crystallization of sodium prasterone sulfate (DHA·SO₃Na·2H₂O) were investigated by thermometric measurements. The anhydrous form (DHA·SO₃Na) was very hygroscopic, and easily transformed to the dihydrate. The dihydrate was in a stable phase under ordinary storage conditions. If the released water molecules were not effectively exhausted in the dehydration process, a liquefaction phenomenon due to the interaction between water molecules and DHA·SO₃Na was observed. The activation energy (ΔE) of the dehydration reaction from the dihydrate to the anhydrous form was determined by an isothermal method and a non-isothermal method (Ozawa method) under a constant water vapor pressure, P_H<SUB>2O</SUB>=14.9 mmHg. ΔE obtained by the isothermal method was 31.5 kcal/mol and ΔE obtained by the Ozawa method was 31.3 kcal/mol.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 29 (5), 1466-1469, 1981

  公益社団法人 日本薬学会

キーワード

• activation energy

詳細情報

• CRID: 1390001204163912448
• NII論文ID: 110003633845
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.29.1466
• ISSN: 13475223
• ISSN: 00092363
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/29/5/29_5_1466/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1982194356
• 本文言語コード: en
• データソース種別:
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