A new route to 4-unsubstituted .BETA.-lactams through ureidomethylation of ketene silyl acetals.

• 池田 潔

• 寺尾 良保

• 関屋 実

抄録

α-Ureidomethylated carboxylates were obtained by the reaction of ketene silyl acetals with benzyl N-(chloromethyl) carbamates in the presence of titanium tetrachloride. Successive hydrogenolysis over palladium-on-charcoal followed by treatment with lithium diisopropylamide gave β-lactams.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 29 (6), 1747-1749, 1981

  公益社団法人 日本薬学会

キーワード

• benzyloxycarbonyl chloride

詳細情報

• CRID: 1390001204167754752
• NII論文ID: 110003633889
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.29.1747
• ISSN: 13475223
• ISSN: 00092363
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/29/6/29_6_1747/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1982193824
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可