Vaticanol C, a Novel Resveratrol Tetramer, Inhibits Cell Growth through Induction of Apoptosis in Colon Cancer Cell Lines.

• Ito Tetsuro

  Gifu Pharmaceutical University

• Akao Yukihiro

  Gifu International Institute of Biotechnology

• Tanaka Toshiyuki

  Gifu Prefectural Institute of Health and Environmental Sciences

• Iinuma Munekazu

  Gifu Prefectural Institute of Health and Environmental Sciences

• Nozawa Yoshinori

  Gifu International Institute of Biotechnology

Abstract

A novel resveratrol tetramer, vaticanol C, isolated from the stem bark of Vatica rassak markedly suppressed cell growth through induction of apoptosis, which was characterized by nuclear changes and DNA ladder formation, in three different human colon cancer cell lines.

Journal

• Biological and Pharmaceutical Bulletin

  Biological and Pharmaceutical Bulletin 25 (1), 147-148, 2002

  The Pharmaceutical Society of Japan

Keywords

• vaticanol C
• apoptosis
• human colon cancer cell
• cell growth
• stilbenoid
• <i>Vatica rassak</i>

Details

• CRID: 1390282679604019200
• NII Article ID: 110003638687
• NII Book ID: AA10885497
• DOI: 10.1248/bpb.25.147
• COI: 1:CAS:528:DC%2BD38XhvVentA%3D%3D
• ISSN: 13475215
• ISSN: 09186158
• PubMed: 11824549
• Web Site: http://www.jstage.jst.go.jp/article/bpb/25/1/25_1_147/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2002157359
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• Abstract License Flag: Disallowed