Screening of Crude Drugs for Influence on Amylase Activity and Postprandial Blood Glucose in Mouse Plasma

Abstract

Screening of crude drugs for inhibitory activity on α-amylase in mouse plasma was performed. Hot water extracts and ethanolic extracts of Arecae Semen, Ephedrae Herba, Malloti Cortex, Rhei Rhizoma and ethanolic extract of Moutan Cortex inhibited enzyme activity in isolated mouse plasma strongly and dose-dependently. However, the effects of these 9 extracts were not observed in the plasma when they were administered intraperitoneally or orally. Ethanolic extract of Arecae Semen also showed a depressive effect on elevation of postprandial blood glucose.

Journal

Biological & pharmaceutical bulletin   [List of Volumes]

Biological & pharmaceutical bulletin 23(10), 1250-1253, 2000-10-01  [Table of Contents]

The Pharmaceutical Society of Japan

References:  14

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Cited by:  7

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Codes

  • NII Article ID (NAID) :
    110003639865
  • NII NACSIS-CAT ID (NCID) :
    AA10885497
  • Text Lang :
    ENG
  • Article Type :
    Journal Article
  • ISSN :
    09186158
  • NDL Article ID :
    5510184
  • NDL Source Classification :
    ZS51(科学技術--薬学)
  • NDL Call No. :
    Z53-V41
  • DOI :
    10.1248/bpb.23.1250
  • Databases :
    CJP  CJPref  NDL  NII-ELS  Journal@rchive 

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