Cytotoxic Activities of Solanum Steroidal Glycosides.

• NAKAMURA Takanori

• KOMORI Chieko

• LEE Yun-yun

• HASHIMOTO Fumio

• YAHARA Shoji

• NOHARA Toshihiro

• EJIMA Akio

抄録

Cytotoxic activities of 20 steroidal glucosides obtained from Solanum genera plants were examined against various cell lines to provide new evidence as follows : 1) As regarding the sugar linkage, the glucosides possessing a β-chacotriosyl moiety were the most effective and the presence of the terminal rhamnosyl residue was required for exhibiting strong activity. 2) As for the aglycone, the glycosides carrying a spirostanol aglycone showed the strongest activity and even an aglycone without a sugar linkage presented considerably strong activity.

収録刊行物

• Ｂｉｏｌｏｇｉｃａｌ　＆　Ｐｈａｒｍａｃｅｕｔｉｃａｌ　Ｂｕｌｌｅｔｉｎ

  Ｂｉｏｌｏｇｉｃａｌ　＆　Ｐｈａｒｍａｃｅｕｔｉｃａｌ　Ｂｕｌｌｅｔｉｎ 19 (4), 564-566, 1996

  公益社団法人 日本薬学会

キーワード

• cytotoxic activity
• Solanum alkaloid
• steroidal glycoside
• β-chacotriosyl moiety

詳細情報

• CRID: 1390282679599680384
• NII論文ID: 110003641214
• NII書誌ID: AA10885497
• DOI: 10.1248/bpb.19.564
• COI: 1:CAS:528:DyaK28XisFShsb0%3D
• ISSN: 13475215
• ISSN: 09186158
• ISSN: http://id.crossref.org/issn/09186158
• PubMed: 8860959
• Web Site: http://www.jstage.jst.go.jp/article/bpb1993/19/4/19_4_564/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1996188078
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可