薬物動態研究におけるトレーサー法の進歩

• 馬場 茂雄

書誌事項

タイトル別名

• Development of Tracer Methods in the Drug Evaluation Study
• ヤクブツ ドウタイ ケンキュウ ニ オケル トレーサーホウ ノ シンポ

抄録

The development of the tracer methods in the drug evaluation study during the past thirty five years was reviewed. Several examples where stable isotope tracer techniques fully demonstrated their advantages were described. The applicability of ¹³C-NMR tracer techniques was discussed. The strategy for the metabolism study of peptides, microplate-radioluminography as a substitute for liquid scintillation counting and a quantitative whole body autoradiography were newly proposed.

収録刊行物

• 薬学雑誌

  薬学雑誌 115 (3), 170-188, 1995

  公益社団法人 日本薬学会

キーワード

• tracer method
• coadministration
• pseudoracemate
• ^<13>C-NMR tracer technique
• peptide tritiation
• radioluminography

詳細情報

• CRID: 1390001206155314944
• NII論文ID: 110003648939
• NII書誌ID: AN00284903
• DOI: 10.1248/yakushi1947.115.3_170
• ISSN: 13475231
• ISSN: 00316903
• ISSN: http://id.crossref.org/issn/00316903
• NDL書誌ID: 3620418
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I3620418
• Web Site: https://www.jstage.jst.go.jp/article/yakushi1947/115/3/115_3_170/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1995220135
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可