緑茶抽出物成分(茶ポリフェノール, カフェイン)のI型アレルギーに対する効果

• 塩崎 哲也

• 杉山 清

• 中里 賢一

• 竹尾 忠一

書誌事項

タイトル別名

• Effect of Tea Extracts, Catechin and Caffeine against Type-I Allergic Reaction
• 緑茶抽出物成分(茶ポリフェノール,カフェイン)の1型アレルギーに対する効果
• リョクチャ チュウシュツブツ セイブン チャポリフェノール カフェイン ノ 1

抄録

The antiallergic effects of green tea, oolong tea, and black tea extracts by hot water were examined. These extracts inhibited the passive cutaneous anaphylaxis (PCA) reaction of rat after oral administration. Three tea catechins, (-)-epigallocatechin (EGC), (-)-epicatechin gallate (ECg), and (-)-epigallocatechin gallate (EGCg) isolated from green tea showed stronger inhibitory effects than that of a green tea extract on the PCA reaction. The inhibitory effects of EGC and EGCg on the PCA reaction were greater than that of ECg. Caffeine also showed a inhibitory effect on the PCA reaction. These results indicate that tea could provide a significant protection against the type-I allergic reaction. These findings also suggest that tea catechins and caffeine play an important role in having an inhibitory effect on the type-I allergic reaction.

収録刊行物

• 薬学雑誌

  薬学雑誌 117 (7), 448-454, 1997

  公益社団法人 日本薬学会

キーワード

• catechin
• caffeine
• antiallergic activity
• type I allergic reaction

詳細情報

• CRID: 1390001206154404480
• NII論文ID: 110003649100
• NII書誌ID: AN00284903
• DOI: 10.1248/yakushi1947.117.7_448
• ISSN: 13475231
• ISSN: 00316903
• ISSN: http://id.crossref.org/issn/00316903
• NDL書誌ID: 4269047
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I4269047
• Web Site: https://www.jstage.jst.go.jp/article/yakushi1947/117/7/117_7_448/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1998002242
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可