書誌事項
- タイトル別名
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- Fast Drug Analysis by Capillary Electrophoresis : Content Uniformity and Assays for Diltiazem Tablets and Trimetoquinol Tablets
- キャピラリー デンキ エイドウニヨルイヤクヒン ジンソク ブンセキ--エンサン
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We applied capillary electrophoresis (CE) to quantify and examine the content uniformity of ingredients of pharmaceutical formulations (diltiazem hydrochloride tablets and trimetoquinol hydrochloride tablets), and also studied separation of enantiomers through the addition of dextrin or cyclodextrin (CD) as a chiral selector. We evaluated these methods in the light of testing procedures and system suitability described in the USP forum. The fast assay and content uniformity of both tablets, including optical purity testing, were performed within 300s. From the results of the system suitability testing, content uniformity and assay, these CE methods were found to be useful as an alternative to the conventional HPLC method.
収録刊行物
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- 薬学雑誌
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薬学雑誌 118 (10), 456-463, 1998
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390001206154123776
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- NII論文ID
- 110003649120
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- NII書誌ID
- AN00284903
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- ISSN
- 13475231
- 00316903
- http://id.crossref.org/issn/00316903
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- NDL書誌ID
- 4568886
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可