Enterococcus faecalis FK-23株加熱死菌体のマウス同系腫瘍に対する抗腫瘍効果  [in Japanese] Antitumor Activity of Enterococcus faecalis FK-23 Preparation against Murine Syngeneic Tumors  [in Japanese]

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Author(s)

Abstract

The antitumor activity of a preparation of heat-killed cells of Enterococcus faecalis, FK-23. Intraperitoneal injection of the preparation prolonged the lifespan of C3H/He N mice which were intraperitoneally inoculated with MM46 mammary carcinoma. Not only intraperitoneal but also oral administration of the FK-23 preparation inhibited the growth of these carcinomas inoculated intradermally. The tumor-bearing mice produced tumor necrosis factor (TNF) in their sera 2 h after intravenous injection of OK432. This TNF level increased after the mice were fed with food supplemented with the FK-23 preparation. Additionally, the FK-23 preparation inhibited the growth of Meth A fibrosarcoma in cyclophosphamide-treated BALB/c mice.

Journal

  • Journal of the Pharmaceutical Society of Japan   [List of Volumes]

    Journal of the Pharmaceutical Society of Japan 113(5), 396-399, 1993-05-25  [Table of Contents]

    The Pharmaceutical Society of Japan

Cited by:  10

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Codes

  • NII Article ID (NAID)
    110003649409
  • NII NACSIS-CAT ID (NCID)
    AN00284903
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    00316903
  • NDL Article ID
    3831630
  • NDL Source Classification
    SD0(薬学)
  • NDL Source Classification
    ZS51(科学技術--薬学)
  • NDL Call No.
    Z19-411
  • Data Source
    CJPref  NDL  NII-ELS 
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