(Na<SUP>+</SUP>+K<SUP>+</SUP>)-Adenosinetriphosphatase(ATPase)アイソザイムの生理的意義

書誌事項

タイトル別名
  • Physiological Functions of (Na<SUP>+</SUP>+K<SUP>+</SUP>)-Adenosinetriphosphatase (ATPase) Isozymes
  • (Na++K+)-Adenosinetriphosphatase(ATPase)アイソザイムの生理的意義
  • Na + + K + Adenosine triphosphatase ATP

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抄録

Since Sweadner demonstrated that there are two isozymes (α and α (+) isoforms) of (Na++K+)-adenosine triphosphatase (ATPase) in the brain about 10 years ago, the isozymes have been extensively studied at biochemical and molecular levels. We started the studies on the isozymes of (Na++K+)-ATPase soon after finding that pyrithiamin, an antimetabolite of thiamin is a selective inhibitor of the α (+) isoform. This review summarizes the previous studies on the isozymes of (Na++K+)-ATPase, which are now classified into α1, α2, and α3.

収録刊行物

  • 薬学雑誌

    薬学雑誌 110 (4), 235-245, 1990

    公益社団法人 日本薬学会

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