Bactobolins, Antitumor Antibiotics from Pseudomonas. II. Synthesis and Biological Activities of Related Compounds

• MUNAKATA TOMOHIKO

Bibliographic Information

Other Title

• Bactobolins, Pseudomonas属細菌由来の抗腫瘍性抗生物質(第2報)誘導体の合成と抗菌活性
• Bactobolins,Pseudomonas属細菌由来の抗腫瘍性抗生物質-2-誘導体の合成と抗菌活性
• Bactobolins Pseudomonasゾク サイキン ユライ ノ コウ

Abstract

Some N-acylbactobolins (VI) were synthesized, and N-L-alanylbactobolin was identified as bactobolin B. The product by Edman's degradation reaction on bactobolin was thought to be a key intermediate for synthetic studies, named bactoboamine which was converted to N-acyl derivatives (IX). Antimicrobial activities of VI and IX were also discussed.

Journal

• YAKUGAKU ZASSHI

  YAKUGAKU ZASSHI 101 (2), 138-147, 1981

  The Pharmaceutical Society of Japan

Keywords

• Pseudomonas sp.
• antimicrobial
• antibiotic
• MIC
• bactobolin
• bactobolamine
• amino acids
• acylation

Details

• CRID: 1390001206126720640
• NII Article ID: 130007274307
• NII Article ID: 110003650124
• NII Book ID: AN00284903
• DOI: 10.1248/yakushi1947.101.2_138
• ISSN: 13475231
• ISSN: 00316903
• NDL BIB ID: 2345171
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I2345171
• Web Site: https://www.jstage.jst.go.jp/article/yakushi1947/101/2/101_2_138/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1982018372
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed