Preparation of Core Particles for Aqueous Film Coating Using Agitation Fluidized Bed.

• WATANO Satoru

• ANDO Kengo

• MIYANAMI Kei

• II Yoshinori

• SASATANI Seiei

書誌事項

タイトル別名

• Preparation of Core Particles for Aqueo

抄録

Core particles used for aqueous film coating were prepared by agitation fluidized bed granulation, and effect of the damping speed on the granule properties of mass median diameter, geometric standard deviation, apparent density, yield friability and specific surface area were investigated. Film coating by an aqueous acylic copolymer (Eudragit NE-30D) was carried out using the core particles granulated under three levels of damping speeds, and the drug release properties of each coated product were identified. Relationship between properties of core particles and the release properties were clarified and the optimal granulation conditions to make optimal core particles for film coating were determined.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 45 (12), 2039-2042, 1997

  公益社団法人 日本薬学会

キーワード

• core particle
• granulation
• agitation fluidized bed
• damping speed
• film coating
• drug relase proterty

詳細情報

• CRID: 1390282679138550144
• NII論文ID: 130003773675
• NII論文ID: 110003662837
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.45.2039
• COI: 1:CAS:528:DyaK1cXltl2k
• ISSN: 13475223
• ISSN: 00092363
• ISSN: http://id.crossref.org/issn/00092363
• NDL書誌ID: 4371075
• PubMed: 9433775
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I4371075
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/45/12/45_12_2039/_pdf
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可