Formation of a Hydroxyl Radical from Riboflavin Sodium Phosphate by Photo-Illumination.

• ISHIMITSU Susumu

• MISHIMA Ikuko

• TSUJI Sumiko

• SHIBATA Tadashi

書誌事項

タイトル別名

• Formation of a Hydroxyl Radical from Ri

抄録

Photo-illumination of riboflavin sodium phosphate (Rp) with phenylalanine produced significant levels of o-tyrosine, m-tyrosine and p-tyrosine as hydroxylated products. The hydroxylation of Rp was pH-dependent, and the maximum rate was around pH 4.5. Replacement of air with nitrogen prevented the formation of tyrosine isomers while the addition of superoxide dismutase or catalase to this system prevented hydroxylation. The tyrosine formation by the system was significantly prevented by hydroxyl radical (HO·) scavengers such as potassium iodide, potassium bromide, thiourea and sodium formate. No free iron and cupric ions were detected in the reaction mixture by inductively-coupled plasma atomic emission spectrometry. Tha above results suggest that the formation of HO· may occur in the photochemical reactoin system in the presence of Rp under aerobic conditions, and that a superoxide radical and hydrogen peroxide may be involved in HO· formation.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 45 (12), 2107-2109, 1997

  公益社団法人 日本薬学会

キーワード

• food color
• riboflavin sodium phosphate
• photochemical reaction
• tyrosine isomer
• phenylalanine
• hydroxyl radical

詳細情報

• CRID: 1390282679137315840
• NII論文ID: 130003773659
• NII論文ID: 110003662850
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.45.2107
• ISSN: 13475223
• ISSN: 00092363
• NDL書誌ID: 4371088
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I4371088
• Web Site: http://www.jstage.jst.go.jp/article/cpb1958/45/12/45_12_2107/_pdf
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可