Studies on Constituents of Crude Drugs. XV. New Pyrrolizidine Alkaloids from Ligularia dentata

• 浅田 善久

  School of Pharmaceutical Sciences, Kitasato University

• 古谷 力

  School of Pharmaceutical Sciences, Kitasato University

抄録

Four new pyrrolizidine alkaloids, ligularidine, neoligularidine, ligularizine and ligularinine, were isolated together with the known compound clivorine from the roots and aerial parts of Ligularia dentata. Their structures were elucidated on the basis of the spectral data and chemical conversion of clivorine into these alkaloids. A useful epoxidation of pyrrolizidine alkaloids was achieved by using performic acid.

収録刊行物

• Chemical & pharmaceutical bulletin

  Chemical & pharmaceutical bulletin 32 (2), 475-482, 1984-02-25

  公益社団法人日本薬学会

キーワード

• Ligularia dentata
• Compositae
• pyrrolizidine alkaloid
• ligularidine
• neoligularidine
• ligularizine
• ligularinine
• clivorine
• epoxidation
• chemical conversion

詳細情報

• CRID: 1572824502292935808
• NII論文ID: 110003663509
• NII書誌ID: AA00602100
• ISSN: 00092363
• Web Site: https://search.jamas.or.jp/link/ui/1985109003
• 本文言語コード: en
• データソース種別:
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