書誌事項
- タイトル別名
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- Highly Selective Intramolecular Heterocyclization and Its Application to Synthesis of Biologically Active Compounds
- コウ センタクテキ ナ ヘテロ カンカ ハンノウ ノ カイハツ ト セイブツ
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Progress toward highly selective intramolecular heterocyclization and its application to the syntheses of biologically active compounds have been reviewed. The highly selective electrophilic heteroatom nucleophiles cyclization of carbon-carbon π-bonds such as iodoiminothiolactonization, iodolactamization, amidomercuration, iodolactonization, and oxylactonization has been developed. Our recent advances taking advantage of stereoselective heterocyclization of homochiral substrates readily available from optical active amine, the Katsuki-Sharpless oxidation, lipase-mediated transesterification, and α-amino acids have provided an attractive entry into the functionalized heterocycles as chiral building blocks. A promising approach to the chiral synthesis of a number of biologically active compounds such as alkaloids, antibiotics, and pheromones has emerged.
収録刊行物
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- 薬学雑誌
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薬学雑誌 113 (11), 737-759, 1993
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390001206154480640
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- NII論文ID
- 110003666172
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- NII書誌ID
- AN00284903
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- ISSN
- 13475231
- 00316903
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- NDL書誌ID
- 3857444
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- データソース種別
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- JaLC
- NDL
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- 使用不可