犬に対する腰椎脊髄造影手技が脊髄に与える影響の検討 Spinal Cord Effects from Lumbar Myelographic Injection Technique in the Dog

犬に対する腰椎脊髄造影時の脊髄腔穿刺が脊髄に与える影響について検討した。5頭の犬に脊髄腔穿刺を行い,脊髄針刺入時および抜去後のCTを撮像した。5例中4例で脊髄針が脊髄を貫通し,抜去後には脊髄実質に造影剤の残存を認めた。撮像後全ての動物に神経学的異常を認めなかったが,病理学的には出血,グリオーシス,軸索変性が観察された。以上,現在行われている腰椎脊髄造影手技は脊髄に損傷をおよぼすことが示唆された。

To characterize spinal cord effects of needle placement using lumbar puncture myelography technique, lumbar puncture was performed in 5 dogs and computed tomography images of the spinal column were acquired in the transverse plane at the level of the puncture site after contrast injection and both before and after needle removal. The spinal cords were punctured during needle placement and parenchymal contrast enhancement was present in 4 of 5 dogs. Although no dogs exhibited overt neurological abnormalities following computed tomographic imaging, hemorrhage, gliosis and axonal degeneration were confirmed microscopically in all subjects. These results suggest that spinal cord morbidity is induced when lumbar myelography is performed using currently accepted technique.