ヒツジの小腸Thiry-Vellaループにおけるブドウ糖吸収に及ぼす灌流速度とブドウ糖濃度の影響(短報)

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  • Effects of perfusion rate and glucose concentration on glucose absorption in intestinal Thiry-Vella loop in sheep.

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10mMブドウ糖を0.5, 1, 2および4ml/minで灌流したときのヒツジ小腸ループにおけるブドウ糖吸収率はそれぞれ77.1±2.2, 54.9±2.3, 31.6±2.1および12.9±0.3%であった. 灌流速度が1ml/minでブドウ糖濃度が5, 10, 20および40mMのときは, それぞれ75.5±1.7, 52.2±2.2, 29.4±1.9および19.5±0.1%であった. 約50%の吸収率が得られたブドウ糖濃度10mM, 灌流速度1ml/minがヒツジ小腸ループにおけるブドウ糖吸収実験の至適な条件であると結論づけた.
The effects of the perfusion rate and glucose concentration in perfusate on glucose absorption in the intestinal Thiry-Vella loop of conscious sheep were studied. When 10 mM glucose was perfused at the rates of 0.5, 1, 2 and 4 ml/min, the absorption rates were 77.1±2.2, 54.9±2.3, 31.6±2.1 and 12.9±0.3%, respectively. When 5, 10, 20 and 40 mM glucose solutions were perfused at 1 ml/min, the absorption rates were 75.5±1.7, 52.2±2.2, 29.4±1.9 and 19.5±0.1%, respectively. We conclude that the perfusion of 10 mM glucose solution at 1 ml/min , in which about a 50% absorption rate was obtained, are the optimal conditions for the study of glucose absorption in the intestinal loop of sheep.

収録刊行物

  • J. Vet. Med. Sci.

    J. Vet. Med. Sci. 56 617-618, 1994

    社団法人日本獣医学会

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