頭蓋骨および脳室の形態的指標を用いたヤギ視床下部神経核への脳定位的アプローチ法の開発

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タイトル別名
  • Cranial and Cerebral-Ventricular Landmarks for Accurate Stereotaxic Approach to Hypothalamic Nuclei in the Goat Brain.
  • 頭蓋骨および脳室の形態的指標を用いたヤギ視床下部神経核への脳定位的アプローチ法の開発〔英文〕
  • ズガイコツ オヨビ ノウシツ ノ ケイタイテキ シヒョウ オ モチイタ ヤギ

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This paper describes a new stereotaxic coordinate system for the goat brain based on cranial landmarks. An osseous triangle (a-b-c) formed by the point of junction of the crista galli with the caudal ventral part of the frontal sinus septum (a), the external occipital protuberance (b), and the midsagittal projection of the external acoustic meatus (c), was measured using lateral radiographs and ventriculographs and showed a constant mathematical relation. The rostral angle was 20.3±1.0 (mean ±SD) degree in 23 goats studied regardless of their cranial size which varied considerably from one animal to another. The hypotenuse length (a-b distance) was found to be a good predictor of the rostral nuchal position of the anterior commissure (AC) and the infundibular recess of the third ventricle (INF), by which the individual variance of the stereotaxic coordinates for a given hypothalamic structure could be compensated. The anterior-posterior distances from the external acoustic meatus was highly correlated with the a-b distance for AC (r=0.88) and INF (r=0.90). Using these cranial landmarks and the method outlined in this paper, uncertainty in coordinate values for AC and INF in the goat brain was reduced considerably in comparison to deviation observed when the ordinary Horsley-Clarke axis (Reid's plane) was employed.

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