封入体肝炎を示したハトから分離されたトリアデノウイルス

DOI 日本農学文献記事索引 Web Site Web Site PubMed 被引用文献4件

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タイトル別名
  • Avian adenovirus isolated from pigeons affected with inclusion body hepatitis.
  • 封入体肝炎を示したハトから分離されたトリアデノウイルス〔英文〕
  • フウニュウタイ カンエン オ シメシタ ハト カラ ブンリサレタ トリアデノ

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Avian adenoviruses were isolated from two pigeons affected with inclusion body hepatitis (IBH) by using chicken embryo liver cell cultures. One of the isolates, designated strain S-PL1, replicated in the cell nuclei forming intranuclear inclusion bodies, showed adenovirus-like morphology by electron microscopy, and cross-reacted serologically with strain SR-48 known as serotype 2 of fowl adenovirus. The strain S-PL1 killed day-old chicks by subcutaneous inoculation, and its 50% chicken lethal dose was 103.8 plaque forming units per bird. Severe lesions characterized with IBH and pancreatitis, were produced in chicks inoculated with the virus. Intranuclear inclusion bodies were also recognized in the liver, pancreas, kidney, proventriculus, small intestine, and caecum. By indirect immunofluorescence test, intranuclear viral antigens were detected in the liver, pancreas and other tissues.

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