A Case of Diabetes Mellitus in Japanese Black Cattle.

DOI Web Site PubMed 被引用文献2件 参考文献22件
  • Hasegawa Takashi
    Veterinary Medical Science, Faculty of Agriculture, Miyazaki University, Miyazaki 889-2192, Japan
  • Uchida Kazuyuki
    Veterinary Medical Science, Faculty of Agriculture, Miyazaki University, Miyazaki 889-2192, Japan
  • Yanase Jun
    Veterinary Medical Science, Faculty of Agriculture, Miyazaki University, Miyazaki 889-2192, Japan
  • Kitazaki Kouhei
    Veterinary Medical Science, Faculty of Agriculture, Miyazaki University, Miyazaki 889-2192, Japan
  • Uchino Yasuo
    Uchino Animal Hospital, Yamada, Kitamorokata, Miyazaki 889-4601, Japan
  • Nakamura Shigemi
    Nosai Miyakonojo, Miyakonojo, Miyazaki 885-0093, Japan
  • Sakimoto Hirohito
    Kagoshima Central Institute of Animal Health, Kagoshima 891-0116, Japan

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A 3 year-old female Japanese Black cattle was diagnosed as diabetes mellitus (DM). Hyperglycemia (295 mg/dl), increase of serum fructosamine (487 μmol/l), elevated glycosylated hemoglobin A1 (GHbA1; 10.9%), low concentration of serum insulin (< 1.0 μU/ml), increased serum glucagon (399 pg/ml), and glucose intolerance (glucose disappearance rate; k=0.53) were noted. On the histopathologic findings in pancreas, insulitis with infiltration of mononuclear cells was found. This case suggests that serum fructosamine and GHbA1 are available parameters for understanding of pathophysiological conditions of bovine DM.

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