Experimental Infection of Calves with Escherichia coli O157:H7

  • OHYA Tatsuo
    Kyushu Research Station, National Institute of Animal Health, 2702 Chuzan-cho, Kagoshima-shi, Kagoshima 891-0105, Japan
  • ITO Hiroya
    Department of Planning and Coordination, National Institute of Animal Health, 3-1-1 Kannondai, Tsukuba-shi, Ibaraki 305-0856, Japan

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Three 3-month-old Japanese Black calves were experimentally infected with Escherichia coli O157:H7 to define the magnitude (CFU/g) and duration of fecal shedding of the organism. In two of the three calves, fecal shedding of E. coli O157:H7 ceased in 5 and 9 weeks. The remaining calf continued shedding E. coli O157:H7 for more than 31 weeks, and the magnitude of the shedding ranged from 101 to 104 CFU/g of feces. The possibility is suggested that a percentage of animals naturally infected with E. coli O157:H7 on farms may become long-term shedders, transmitting the organism to other animals in the herd and to the proximate environment.

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