The Risk of Contrast Media-Induced Ventricular Fibrillation is Low in Canine Coronary Arteriography with Ioxilan.

• MISUMI Kazuhiro

  Department of Veterinary Medicine, Kagoshima University, 21-24 Korimoto 1-chome, Kagoshima 890-0065, Japan

• TATENO Oki

  Department of Veterinary Medicine, Kagoshima University, 21-24 Korimoto 1-chome, Kagoshima 890-0065, Japan

• FUJIKI Makoto

  Department of Veterinary Medicine, Kagoshima University, 21-24 Korimoto 1-chome, Kagoshima 890-0065, Japan

• MIURA Naoki

  Department of Veterinary Medicine, Kagoshima University, 21-24 Korimoto 1-chome, Kagoshima 890-0065, Japan

• SAKAMOTO Hiroshi

  Department of Veterinary Medicine, Kagoshima University, 21-24 Korimoto 1-chome, Kagoshima 890-0065, Japan

書誌事項

タイトル別名

• risk of contrast media induced ventricular fibrillation is low in canine coronary arteriography with ioxilan

抄録

Previous studies have proposed that sodium supplement to nonionic contrast media (CM) can decrease the risk of ventricular fibrillation (VF). This study was designed to compare the occurence of VF induced by ioxilan (containing 9 mmol/LNa⁺) with other nonionic CMs. After wedging a catheter in the right coronary artery, test solutions including ioxilan, ioversol, iomeprol, and iopromide were infused for 30 sec at the rate of 0.4 ml/sec or until VF occurred. Then, incidence of VF, contact time (i.e. the time required to produce VF), and QTc were measured. Also, the CMs other than ioxilan were investigated at sodium levels adjusted to 9 and 20 mmol/L Na⁺. The incidence of VF with ioxilan (0% ) was the lowest of all. In the other CMs, the incidence decreased in accordance with increase of sodium. Iomeprol and iopromide showed significant reduction of VF incidence at the sodium level of 20 mmol/L. The higher sodium supplements also prolonged the contact times. The increase of QTc was the greatest in ioxilan. Ioxilan has the least arrythmogenic property among the current low-osmolality nonionic CMs. This property might be attributable to an optimal sodium concentration of 9 mmol/L in the CM.

収録刊行物

• Ｔｈｅ　Ｊｏｕｒｎａｌ　ｏｆ　Ｖｅｔｅｒｉｎａｒｙ　Ｍｅｄｉｃａｌ　Ｓｃｉｅｎｃｅ

  Ｔｈｅ　Ｊｏｕｒｎａｌ　ｏｆ　Ｖｅｔｅｒｉｎａｒｙ　Ｍｅｄｉｃａｌ　Ｓｃｉｅｎｃｅ 62 (4), 421-426, 2000

  公益社団法人 日本獣医学会

キーワード

• contrast media
• coronary arteriography
• ioxilan
• ventricular fibrillation

詳細情報

• CRID: 1390001206427243392
• NII論文ID: 110003920335
• NII書誌ID: AA10796138
• DOI: 10.1292/jvms.62.421
• COI: 1:CAS:528:DC%2BD3cXjvVWhtrk%3D
• ISSN: 13477439
• ISSN: 09167250
• NDL書誌ID: 5369478
• PubMed: 10823730
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I5369478
• Web Site: http://www.jstage.jst.go.jp/article/jvms/62/4/62_4_421/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2000199154
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可