臨床病理学:健常犬のリンパ球幼若化反応におよぼす遺伝子組換え型ヒト顆粒球コロニー刺激因子の影響(短報)

• 長谷川 貴史

  宮崎大学農学部附属家畜病院

• 猪俣 生輝

  宮崎大学農学部附属家畜病院

書誌事項

タイトル別名

• Effect of Recombinant Human Granulocyte Colony Stimulating Factor on Lymphocyte Blastogenesis in Healthy Dogs.

抄録

Effects of recombinant human granulocyte colony−stimulating factor(rhG−CSF)on the number and blastogenesis of lymphocytes were evaluated in clinically healthy dogs treated subcutaneously with rhG−CSF at a dose of 2.5 μg/kg for 3 days.Significant increases in the number of leukocytes and segmented neutrophils were observed after the administration of rhG−CSF.The number of lymphocytes also increased on days 1 and 2 after the treatment.Activities of phytohemagglutinin, concanavalin A, and pokeweed mitogen−induced lymphocyte blastogenesis(LB)were augmented to twice the pretreatment levels by the administration of rhG−CSF.These results suggested that administration of rhG−CSF activated lymphocyte functions such as LB in healthy dogs.

収録刊行物

• Ｔｈｅ　Ｊｏｕｒｎａｌ　ｏｆ　Ｖｅｔｅｒｉｎａｒｙ　Ｍｅｄｉｃａｌ　Ｓｃｉｅｎｃｅ

  Ｔｈｅ　Ｊｏｕｒｎａｌ　ｏｆ　Ｖｅｔｅｒｉｎａｒｙ　Ｍｅｄｉｃａｌ　Ｓｃｉｅｎｃｅ 62 (11), 1205-1207, 2000

  公益社団法人 日本獣医学会

キーワード

• canine
• lymphocyte blastogenesis
• recombinant human granulocyte colony-stimulating factor

詳細情報

• CRID: 1390001206425489536
• NII論文ID: 110003920495
• NII書誌ID: AA10796138
• DOI: 10.1292/jvms.62.1205
• COI: 1:CAS:528:DC%2BD3cXovVGgt74%3D
• ISSN: 13477439
• ISSN: 09167250
• NDL書誌ID: 5577137
• PubMed: 11129867
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I5577137
• Web Site: http://www.jstage.jst.go.jp/article/jvms/62/11/62_11_1205/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2001072146
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可