Olfactory Neuroepithelioma in a Dog: An Immunohistochemical and Electron Microscopic Study.
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- HARA Kazuya
- Department of Veterinary Pathology, Tottori University
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- SHIMADA Akinori
- Department of Veterinary Pathology, Tottori University
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- MORITA Takehito
- Department of Veterinary Pathology, Tottori University
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- SAWADA Masumi
- Department of Veterinary Pathology, Tottori University
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- UMEMURA Takashi
- Laboratory of Comparative Pathology, Graduate School of Veterinary Medicine, Hokkaido University
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A case of olfactory neuroepithelioma was investigated electron microscopically and immunohistochemically. The tumor mass was found in the nasal cavities of a 10-year-old female dog, which showed epistaxis, nasal discharge and facial swelling. The tumor tissue consisted of tubular structure of cuboidal to columnar cells and compactly arranged nests of small cells surrounded by a fibrovascular stroma. Mitotic figures were frequently observed. Immunohistochemically, the tumor cells frequently showed positive for neurofilament protein, synaptophysin and/or carnosine in addition to keratin. Ultrastructurally, tight junction was observed between the tumor cells. No dense-cored secretory granules were shown in the tumor cells. These findings indicated that the present tumor had neuronal and epithelial features probably originating from the olfactory epithelium.
収録刊行物
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- The Journal of Veterinary Medical Science
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The Journal of Veterinary Medical Science 64 (4), 391-393, 2002
公益社団法人 日本獣医学会
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詳細情報 詳細情報について
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- CRID
- 1390282681402342272
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- NII論文ID
- 110003920863
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- NII書誌ID
- AA10796138
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- COI
- 1:STN:280:DC%2BD383ntlOisg%3D%3D
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- ISSN
- 13477439
- 09167250
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- NDL書誌ID
- 6151603
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- PubMed
- 12014590
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可