ウィスターラットの週齢および性差によるベネズエラ糞線虫感染感受性の変化

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  • RIVERO Juan C.
    Department of Veterinary Teaching Hospital and Internal Medicine, Faculty of Agriculture, Miyazaki University
  • INOUE Yoichi
    Department of Veterinary Teaching Hospital and Internal Medicine, Faculty of Agriculture, Miyazaki University
  • MURAKAMI Noboru
    Departmet of Veterinary Physiology, Faculty of Agriculture, Miyazaki University
  • HORII Yoichiro
    Department of Veterinary Teaching Hospital and Internal Medicine, Faculty of Agriculture, Miyazaki University

書誌事項

タイトル別名
  • Age- and Sex-Related Changes in Susceptibility of Wistar Rats to Strongyloides venezuelensis Infection.
  • Age- and Sex- Related Changes in Susceptibility of Wistar Rats to Strongyloides venezuelensis Infection(NOTE)

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The effects of host age and sex on susceptibility to Strongyloides venezuelensis in Wistar rats were examined by counting larvae recovered from the lungs of animals 3 days after infection. The susceptibility of female rats to S. venezuelensis rapidly decreased with age and elevated estrogen. Resistance in female rats inoculated at 6 and 10 weeks of age was nine and twenty-fold higher, respectively than that in the youngest group (3 weeks). In contrast, the susceptibility of male animals was lowest in the youngest group, then increased with age and elevated testosterone. Sex differences in susceptibility were not evident in the youngest group, but became apparent with age.

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