犬のモノアミン酸化酵素B遺伝子におけるシステインへからアルギニンのアミノ酸置換を伴う一塩基多型の同定
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- HASHIZUME Chie
- Laboratory of Veterinary Ethology, The University of Tokyo
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- MASUDA Koji
- Laboratory of Veterinary Ethology, The University of Tokyo
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- MOMOZAWA Yukihide
- Laboratory of Veterinary Ethology, The University of Tokyo
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- KIKUSUI Takefumi
- Laboratory of Veterinary Ethology, The University of Tokyo
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- TAKEUCHI Yukari
- Laboratory of Veterinary Ethology, The University of Tokyo
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- MORI Yuji
- Laboratory of Veterinary Ethology, The University of Tokyo
書誌事項
- タイトル別名
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- Identification of an Cysteine-to-Arginine Substitution Caused by a Single Nucleotide Polymorphism in the Canine Monoamine Oxidase B Gene
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Monoamine oxidase B catalytically oxidizes biogenic amines such as phenylethylamine and dopamine, and its activity is presumed to be related to particular behavioral traits. In this study, we first identified a single nucleotide polymorphism (T199C) located on the putative third exon of the canine monoamine oxidase B gene, which causes an amino acid substitution from cysteine to arginine. We then examined the allelic frequencies in five dog breeds (Golden Retriever, Labrador Retriever, Maltese, Miniature Schnauzer, and Shiba) and found significant variation among them. The present results suggest that analysis of the monoamine oxidase B polymorphism could be a useful means of elucidating the genetic background of breed-specific behavioral characteristics in dogs.<br>
収録刊行物
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- Ｔｈｅ Ｊｏｕｒｎａｌ ｏｆ Ｖｅｔｅｒｉｎａｒｙ Ｍｅｄｉｃａｌ Ｓｃｉｅｎｃｅ
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Ｔｈｅ Ｊｏｕｒｎａｌ ｏｆ Ｖｅｔｅｒｉｎａｒｙ Ｍｅｄｉｃａｌ Ｓｃｉｅｎｃｅ 67 (2), 199-201, 2005
公益社団法人 日本獣医学会
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詳細情報 詳細情報について
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- CRID
- 1390282681403566848
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- NII論文ID
- 110003963703
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- NII書誌ID
- AA10796138
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- ISSN
- 13477439
- 09167250
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- NDL書誌ID
- 7261169
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- PubMed
- 15750319
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- IRDB
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可