歯周ポケット貼布薬グアヤコール配合ヨードグリコールパスタの抗菌性について

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  • Antimicrobial effect on oral bacteria of iodglycol paste containing 20% guaiacol.

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The purpose of this study was to evaluate the antimicrobial activity of iodglycol paste containing 20% guaiacol (Gu-JG), and of iodglycol paste (JG) and guaiacol (Gu), against sixteen aerobic and anaerobic microorganisms using an agar-well method. The minimum inhibitory concentration of the three agents and the antimicrobial activity of Gu were also determined.<BR>The results obtained were as follows:<BR>1. The sucseptibility of the organisms tested against Gu-JG was higher than that of JG. Gu showed antimicrobial activity similar to or higher than Gu-JG or JG.<BR>2. The minimum inhibitory concentration of Gu to six human oral microorganisms was the lowest of the three.<BR>3. The antimicrobial effect of Gu on the tested organisms covered a range of 0.1% to 1%.<BR>Thus, Gu-JG, JG and Gu had antimicrobial activity against oral bacteria, suggesting that Gu-JG exerts a useful effect against oral microorganisms in vivo in periodontal pockets.

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