抄録
数種類の洗口剤を用いて,初期のプラーク形成抑制効果に関して臨床的検討を行った。歯周疾患の徴候のない25〜35歳の成人8名を被験者とした。実験開始前,14日間にわたり専門家による歯面清掃と口腔衛生指導を行った。実験開始時から全ての機械的歯面清掃を中止し,洗口剤10mlで1日2回1分間の洗口を4日間行った。実験開始時と4日後,全歯面に対してPlaque lndex(P1I)を用い診査を行った。4日目の診査後,専門家による歯面清掃と被験者自身によるブラッシングを再開し,10日後に再ぴ歯面清掃を中止し,他の洗口剤により4日間洗口を行った。以上の方法で,1)蒸留水(DW),2)0.12%グルコン酸クロル・ヘキシジン水溶液(CHX),3)酸化電位水(AW),4)0.1%フッ化第一スズ水溶液(SnF_2),5)0.02%塩化セチルピリジニウム含有洗口剤(CPC)の5種類の洗口剤を用いて検討を行った。全歯面におけるP1I 値は CHX で0.75,AW 1.21,SnF_2 1.20,CPC 1.55,DW 1.61であった。これらを比較検討したところ,CHX と他の全ての洗口液,AW と CPC とDW,SnF2とCPCとDWの間に統計学的有意差が認められた。また,全ての洗口剤において前歯部のp1I 値は小臼歯部,大臼歯部のものよりも低く,頬舌側面のp1I値は隣接面よりも低かった。
By using several kinds of mouthrinse, its inhibitory effect on the early plaque formation was examined for clinical consideration. Eight adult volunteers aged 25 to 35 years old with apparently healthy gingiva showing no sign of periodontal disease were enrolled in this study. For 14 consecutive days prior to the initiation of study, tooth surface cleaning and oral hygiene instruction were performaed by a dentist. All of these mechanical cleaning manipulations were abandoned at the beginning of experiment and mouthrinsing was performed with 10 ml of different mouthrinses for one minute a time, twice a day. At the beginning of experiment and again on Day 4, the tooth surface was totally examined by means of Silness and Loe's Plaque Index (P1I). After ecamination on Day 4, tooth surface cleaning by the dentist and brushing by the subject were restarted, followed by dincontinuation of tooth cleaning after 10 days and than mouthrinsing with other mouthrinsing agents for subsequent 4 days. Five kinds of mouthrinse were used for this purpose, including 1) distilled water (DW) , 2) O . 12%o chlorhexidine (CHX), 3) acid water prepared by an electrolysis (AW) , 4) 0.1% stannous fluoride (SnF_2) and 5) O.02% cetylpyridium chloride-containing mouthrinse (Dentor Systema, Lion) (CPC) . Various regions such as whole tooth surface, maxilla, mandible, anterior teeth, premolar, molar, adjacent surface and buccolingual side were examined for comparison. The average P1I value was 0.75 for CHX, 1.21 for AW, 1.20 for SnF_2, 1.55 for CPC and 1.61 for DW. A statistical siguificant differences was observed between CHX and other individual mouthrinses, between AW and CPC or DW as well as between SnF_2 and CPC or DW. Further, concerning all mouthrinses examined, the P1I value for anterior tooth region was lower than those of premolar and molar regions and the value for buccolingual region was lower than that for adjacent surface. J. Jpn. Soc. Periodontol., 43 : 283-288, 2001.
