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Abstract
Three new dimeric benzofuran derivatives, ligulacephalins A (1), B (2) and C (3), were isolated from the roots of Ligularia stenocephala MATSUM. et KOIDZ. (Compositae) together with three known compounds, 5, 6-dimethoxy-2-isopropenylbenzofuran (4), euparin (5) and (R)-(-)-hydroxytremetone (6). The structures of the new compounds were determined by spectroscopic evidence. The chiral HPLC analysis demonstrated that 1-3 occurred as a racemate. The absolute configurations of each enantiomer from 1-3 were elucidated on the basis of circular dichroism (CD) data.
Journal
- Chemical & pharmaceutical bulletin [List of Volumes]
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Chemical & pharmaceutical bulletin 53(12), 1555-1558, 2005-12-01 [Table of Contents]
The Pharmaceutical Society of Japan
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