生体分子-半導体表面間相互作用の分子動力学シミュレーション(S24-1 バイオ・ナノ流動ダイナミクス(1),S24 バイオ・ナノ流動ダイナミクス)

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  • Molecular dynamics simulation on interactions between biomolecules and semiconductor substrates

抄録

By investigating the interactions between Green Fluorescent Protein (GFP) and Si substrates using molecular dynamics simulation, we got the following results. GFP adsorbs on the hydrophobic substrate directly, and on the hydrophilic substrate via water molecules. GFP-hydrophobic substrate attractions are stronger than GFP-hydrophilic substrate attractions. Flexibility of GFP is reduced when GFP adsorbs on the Si substrate.

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