<Rapid communication>Molecular DNA Analysis of Methicillin-resistant Staphylococcus aureus (MRSA) Infection in a Neonatal Intensive Care Unit

    • TAKIZAWA Yoko
    • Division of Bacteriology, Department of Infectious Disease Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences:Division of Respiratory Medicine, Department of Homeostatic Regulation and Development, Niigata University Graduate School of Medical and Dental Sciences
    • TANEIKE Ikue
    • Division of Bacteriology, Department of Infectious Disease Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences
    • NAKAGAWA Saori
    • Division of Bacteriology, Department of Infectious Disease Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences
    • ISHII Shiro
    • Division of Obstetrics and Gynecology, Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences
    • KURABAYASHI Takumi
    • Division of Obstetrics and Gynecology, Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences
    • TANAKA Kenichi
    • Division of Obstetrics and Gynecology, Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences
    • GEJYO Fumitake
    • Division of Respiratory Medicine, Department of Homeostatic Regulation and Development, Niigata University Graduate School of Medical and Dental Sciences
    • YAMAMOTO Tatsuo
    • Division of Bacteriology, Department of Infectious Disease Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) infection in neonatal intensive care units (NICUs) has become a serious problem in Japan. MRSA nosocomial transmissions occurring in an NICU during 2001 and 2002 were investigated by pulsed-field gel electrophoresis and PCR. MRSA from a nosocomial transmission with incidences of neonatal toxic shock syndrome-like exanthematous disease (NTED) produced type II coagulase and possessed multiple superantigenic toxin genes for toxic shock syndrome toxin (TSST)-1, staphylococcal enterotoxin (SE) C, SEG, and SEI. MRSA from a nosocomial transmission with incidences of staphylococcal scalded skin syndrome (SSSS) was clonally distinct from the NTED-associated MRSA, produced type I coagulase, and possessed only the exfoliative toxin B gene (no previous superantigenic toxin genes were detected).

Journal

Acta medica et biologica   [List of Volumes]

Acta medica et biologica 51(3), 103-109, 2003-09  [Table of Contents]

Niigata University

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