Periodo reproductor y madurez sexual de la sardina Sardina pilchardus (Walbaum, 1792) en aguas de Gran Canaria (Islas Canarias)

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Plasma diamine oxidase (DAO) activity after heparin injection, a circulatory marker for the intestinal mucosal integrity, was evaluated shortly after major abdominal surgery. DAO activity was measured by high-performance liquid chromatography method after 50 units/kg of heparin injection after esophagectomy in 8 patients, total gastrectomy in 16 patients, and pancreatectomy in 7 patients. Blood samples were collected before and at 2, 10, and 30 days after operation. Postheparin DAO activity at the 2nd day after operation decreased to 60% of the value before operation (p<0.05), then recovered gradually until the 30th day. The activity decreased in cases after esophagectomy and pancreatectomy (p<0.01). It is suggested that the intestinal mucosal integrity decreases in the early course after the major gastroenterological surgery.

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