抗体産生関連リンパ球諸機能の歯周病病態への関わりの研究

DOI 被引用文献2件

書誌事項

タイトル別名
  • Studies on the Status of Periodontal Disease from the Lymphocytes Functions Concerned with Immunoglobulin Synthesis.

この論文をさがす

抄録

The purpose of these studies was to assess the relationship between factors in the immune network concerned with immunoglobulin synthesis. We examined immunoglobulin production, lymphocyte subset ratios and lymphocyte function using peripheral blood mononuclear cells from 50 subjects consisting of 32 patients with periodontal disease and 18 periodontally healthy subjects. On the basis of serum antibody titers to periodontal bacteria, patients were classified into two groups characterized by either low or high titers. Patients had lower proportional counts of suppressor/cytotoxic T cells and higher immunoglobulin productivity than healthy subjects. Subjects with an elevated or decreased ratio of lymphocyte subsets and lymphocyte functions were detected more frequently among patients, irrespective of antibody titers.<BR>However, a wide distribution of values was observed among subjects in all of the examination. Based on the results obtained, it appears that lymphocyte functions concerned with humoral immune response vary widely among subjects, and each feature must be clarified individually.

収録刊行物

被引用文献 (2)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ