イヌＩＩＩ級根分岐部病変に骨移植を応用したＧＴＲ法の創傷治癒に関する研究

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  • Periodontal Healing Following Guided Tissue Regeneration Technique with Bone Grafts on Class III Furcation Defects in Dogs.

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This study was designed to evaluate the effect of the guided tissue regeneration technique using defatted decalcified freeze-dried bone matrix powder on the healing of furcation defects.<BR>Three mongrel dogs were used. Class III furcation defects were produced in the 3 rd and 4 th lower premolars. Dogs were treated by two different surgical methods. On the control side, the guided tissue regeneration technique alone was used, and on the experimental side, the guided tissue regeneration technique plus bone graft were used.<BR>Fourteen weeks after the operation the dogs were sacrificed, and histopathological studies were performed. The results were as follows;<BR>I. Control side<BR>1. Connective tissues had filled the furcation defects.<BR>2. Minimal amounts of bone regeneration were observed at the bottom of the furcation defects.<BR>3. Formation of new cementum was observed all around the fornix of the furcation. II. Experimental side<BR>1. Furcation defects were completely covered by regenerated bone which was separated from the root surface.<BR>2. Formation of new cementum was observed all around the fornix of the furcation.<BR>3. A functionally oriented periodontal ligament had become reestablished in the apical portion.<BR>These findings suggest that the guided tissue regeneration technique with bone grafting may increase bone regeneration of furcation defects.

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