茶葉成分含有洗口剤の実験的歯周炎に対する効果  [in Japanese] The Effect of Oral Rinses Extracted from Japanese Tea on the Experimental Gingivitis in Man  [in Japanese]

古くから日本茶には抗う蝕,口臭予防作用があることが知られ,その有効成分のカテキンは,抗菌,抗酸化作用を示すことが報告されている。そこで,化学的プラークコントロール剤としての茶葉成分の有用性について検索した。被験者は15歳から25歳の男女45名とし,研究開始までにPlI, GIを0の状態とした。被験者を2群に分け,試験Iは,試験期間は,茶エキス1.2%含有洗口剤(以下カテキン),対照期間は,カテキンから茶エキスのみを除外した洗口剤,試験IIは,試験期間はカテキン,対照期間は蒸留水による洗口を行わせた。期間中は,歯ブラシおよびその他の清掃機具の使用を中止させた。臨床検査は,試験開始後0, 3, 7, 10日目にPlI, GI, GCF量,細菌学的検査,口臭を測定した。その結果,カテキン群においてプラーク増加抑制,歯肉炎抑制および,口臭抑制傾向を示し,茶葉成分が化学的プラークコントロール剤として有用であることが示唆された。

Japanese green tea has long been known to have an anticarious action and a halitosis-preventing action. The active ingredient, catechin, has been reported to have antibacterial and antioxidant actions. Accordingly, we investigated the usefulness of green tea leaf ingredients as a chemical plaque control agent. The subjects were 45 male and female volunteers ranging from 15 to 25 years of age, in whom the Plaque Index and Gingival Index were controlled to zero before initiation of the study. The subjects were divided into two groups. In group I , the subjects were asked to rinse their oral cavities with a mouthwash containing 1.2% green tea extract (catechin) during the study period, and using a mouthwash produced by eliminating tea extracts alone from catechin. Subjects in group II rinsed their oral cavities with catechin during the study period, and distilled water during the control period. The subjects were not allowed to use a toothbrush or other cleaning devices during these periods. The following clinical parameters were measured 0, 3, 7 and 10 days after initiation of the study: 1) Plaque Index, 2) Gingival Index, 3) Gingival crevicular fluid level, 4) Bacterial flora, and 5) Halitosis. As a result, suppression of plaque increase, prevention of gingivitis and prevention of halitosis were noted after oral rinsing with the mouthwash containing tea leaf extracts. These findings indicate that Japanese green tea leaf ingredients are useful as a chemical plaque control agent.