超電解イオン水のプラーク形成抑制効果について  [in Japanese] Inhibitory Effect of Acid Electrolyzed Water on Plaque Formation  [in Japanese]

本研究の目的は,超電解イオン水の洗口によるプラーク形成抑制効果を検討することである。臨床的に健康な歯周組織を有する7名(男性4名,女性3名)を被験者とし,実験開始にあたって全顎のGingival Index (GI)および上顎両側犬歯の歯肉溝滲出液(Gingival Crevicular Fluid: GCF)量の診査を行いエアーポリッシャーおよびハンドスケーラーにより全歯面上のプラークを除去した。口腔清掃を停止し,洗口(1日4回,約150mlにて1分間)のみを4日間行った。2日および4日後に上顎両側小臼歯の頬側の歯肉縁上プラークを採取し,歯面上の生菌数をColony forming unit (CPU)により調べた。また,4日後のGI, GCF unitsおよび全顎のPlaque Index (PII)の変化も検討した。コントロールとして,ポビドンヨード,生理食塩水を用いた。4日目のGIにおいては,超電解イオン水では生理食塩水に比べ有意に低い値を示した。一方,4日目のPlIは,超電解イオン水では,生理食塩水と同程度であり,ポビドンヨードに比べ有意に高いプラーク付着を示した。GCF量に関しては,各被験液間で有意な差はみられなかった。超電解イオン水における2日目のCFUは,ポビドンヨードと同様,生理食塩水に比べ有意に低い値を示した。4日目におけるCFUは,各被験液間で有意な差はみられなかった。以上のことから洗口剤として超電解イオン水を使用した際, 2日目においてはポビドンヨードと同様の殺菌作用を示すが, 4日目においてはいずれも殺菌作用は低く,また超電解イオン水のプラーク形成抑制作用はポビドンヨードよりもやや劣ると思われる。

The purpose of this study was to evaluate the inhibitory effect of acid electrolyzed water on plaque formation. Seven healthy subjects participated in this study. Before the experiment, the Gingival Index (GI) of all teeth and Gingival Crevicular Fluid (GCF) units of the upper canines were examined, and all teeth were cleaned with an air polisher and hand scaler. The subjects were asked to stop their own daily oral hygiene procedures for 4 days and to rinse with 150ml of acid electrolyzed water 4 times daily, one minute each time. Two and 4 days later, supragingival plaque was collected from the upper 1st or 2nd premolars and colony forming unit (CPU) were assayed. After 4 days, GI, GCF units, and Plaque Index (PlI) were recorded. Povidone iodine solution and physiological saline were used as positive and negative controls, respectively. GI was significantly lower in the acid electrolyzed water group than in the physiological saline group. PlI in the acid electrolyzed water group was the same as in the physiological saline group, and significantly higher than in the povidone iodine solution group. There were no significant differences in GCF units among the three groups. After 2 days, CFU in the acid electrolyzed water group was significantly lower than in the physiological saline group, and the same as in the povidone iodine solution group. However, no significant improvements were observed after 4 days. These results suggested that both acid electrolyzed water and povidone iodine solution had bactericidal activity after 2 days, but were no longer effective after 4 days, and that acid electrolyzed water was not as effective as povidone iodine solution for plaque inhibition after 4 days.