未破裂脳動脈瘤クリッピング術前後の3D-SSP解析による脳血流評価とMini-Mental State Examination (MMSE)による高次機能評価  [in Japanese] Cerebral Blood Flow Study with 3D-SSP and Neuropsychological Evaluation by Mini-Mental State Examination (MMSE) Before and After Clipping of Unruptured Cerebral Aneurysm  [in Japanese]

We evaluate the influence of surgery for unruptured aneurysms on cerebral blood flow and neuropsychological estimate. We evaluated the cases of 28 consecutive patients with unruptured cerebral aneurysm treated with direct surgery accompanied by craniotomy. Before and after surgery, MRI, ^<123>I-IMP-SPECT with 3D-SSP analysis and MMSE were performed. There was not a significant decrease in MMSE. In ^<123>I-IMP-SPECT, it was recognized that the cerebral blood flow was decreased at the frontal operculum of operative site. These results indicate that careful neuropsychological evaluation is essential to make a favorable treatment plan for unruptured aneurysms.