Chymotrypsin Inhibitory Triterpenoids from Silybum marianum

    • AHMED Ejaz
    • International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi
    • MALIK Abdul
    • International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi
    • FERHEEN Sadia
    • Pharmaceutical Research Center, PCSIR Laboratories, Karachi Complex
    • AFZA Nighat
    • Pharmaceutical Research Center, PCSIR Laboratories, Karachi Complex
    • AZHAR-UL-HAQ
    • International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi
    • LODHI Muhammad Arif
    • International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi
    • CHOUDHARY Muhammad Iqbal
    • International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi

Abstract

Marianine, the new lanostane triterpene (1) and marianosides A (2) and B (3) have been isolated from the whole plant of Silybum marianum. Their structures were elucidated on the basis of extensive analysis of their one dimensional and two dimensional nuclear magnetic resonance (1D, 2D-NMR) spectral data. All inhibited chymotrypsin in a concentration-dependent manner.

Journal

Chemical & pharmaceutical bulletin   [List of Volumes]

Chemical & pharmaceutical bulletin 54(1), 103-106, 2006-01-01  [Table of Contents]

The Pharmaceutical Society of Japan

References:  28

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Codes

  • NII Article ID (NAID) :
    110004820333
  • NII NACSIS-CAT ID (NCID) :
    AA00602100
  • Text Lang :
    ENG
  • Article Type :
    NOT
  • ISSN :
    00092363
  • NDL Article ID :
    7756811
  • NDL Source Classification :
    ZS51(科学技術--薬学) // ZP1(科学技術--化学・化学工業)
  • NDL Call No. :
    Z53-D167
  • Databases :
    CJP  NDL  NII-ELS  J-STAGE 

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