Hepatitis B Virus Inhibiting Constituents from Herpetospermum caudigerum

    • YUAN Hai-Long
    • 302 Hospital of PLA&PLA Institute of Chinese Materia Medica
    • YANG Ming
    • Key Lab of Modern Preparation of TCM, Ministry of Education
    • LI Xian-Yi
    • 302 Hospital of PLA&PLA Institute of Chinese Materia Medica
    • You Rong-Hui
    • Key Lab of Modern Preparation of TCM, Ministry of Education
    • LIU Yi
    • Acadamy of Pharmacy, Chengdu University of TCM
    • ZHU Jun
    • Acadamy of Pharmacy, Chengdu University of TCM
    • XIE Huan
    • Acadamy of Pharmacy, Chengdu University of TCM
    • XIAO Xiao-He
    • 302 Hospital of PLA&PLA Institute of Chinese Materia Medica

Abstract

From the ethanol extract of the seeds of Herpetospermum caudigerum wall, one new lignan compound 1, was isolated and characterized along with three known compounds 2, 3 and 4. The structure elucidation of the isolated new compound was performed on the basis of spectroscopic and chemical evidence. The structures of known compounds were determined by comparison of spectral data and physical data with those previously reported. The activity inhibiting hepatitis b virus was evaluated. Preliminary studies showed that compound 1 and 2 displayed promising inhibitory potential against hepatitis b virus.

Journal

Chemical & pharmaceutical bulletin   [List of Volumes]

Chemical & pharmaceutical bulletin 54(11), 1592-1594, 2006-11-01  [Table of Contents]

The Pharmaceutical Society of Japan

References:  11

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Codes

  • NII Article ID (NAID) :
    110004836482
  • NII NACSIS-CAT ID (NCID) :
    AA00602100
  • Text Lang :
    ENG
  • Article Type :
    NOT
  • ISSN :
    00092363
  • NDL Article ID :
    8516675
  • NDL Source Classification :
    ZS51(科学技術--薬学) // ZP1(科学技術--化学・化学工業)
  • NDL Call No. :
    Z53-D167
  • DOI :
    10.1248/cpb.54.1592
  • Databases :
    CJP  NDL  NII-ELS  J-STAGE