花粉大量飛散ピーク時における花粉症患者のQOL : SF-8を用いて  [in Japanese] QUALITY OF LIFE IN PATIENTS WITH JAPANESE CEDAR POLLINOSIS : USING THE SF-8 HEALTH STATUS QUESTIONNAIRE (JAPANESE VERSION)  [in Japanese]

【目的】スギ花粉症患者のQOLについてSF-8を用いて調査し,その有用性を検討した.【方法】2005年のスギ花粉飛散ピーク時に,大阪府・兵庫県の診療所においてスギ花粉症で受診した患者に,SF-8によるQOLを含むアンケート調査を行い,シーズン中に全く治療を受けていない症例のうち有効回答の得られた204名を解析対象とした.【結果】SF-8の国民標準値と比較すると,スギ花粉症患者では精神面のQOLが有意に低値を示した.特に,女性では有意差が認められた.男女別に比較すると,SF-8のサマリースコアおよびほとんどのドメインにおいて,女性の方が身体面・精神面共にQOLが障害されていた.年齢別に分析すると,加齢に伴い,特に身体面でのQOLが低下した.また,くしゃみや鼻づまりなどの症状の重症化に伴い,精神面においてQOLの低下が認められた.【結語】本研究では,花粉飛散ピーク時のQOLについて,従来のSF-36を用いた研究と同様の結果が得られた.SF-8は,感度は良くないが,より短時間で行うことができ,大人数の症例検討や他疾患との比較において,今後有用な質問票になると示唆された.

Background: The number of patients with Japanese cedar pollinosis (JCP) is increasing, and now, has extended up to about 15% of the Japanese. It is reported that the QOL is an important outcome in the JCP treatment. This study aimed to evaluate the QOL in patients with JCP by means of the SF-8 Health Survey (Japanese Version), a new, even shorter generic health survey. Methods: 411 patients with JCP who visited 10 ENT clinics in Osaka from March 14 to March 26 (peak pollen season) were questioned, and 204 patients without any treatments in this season were engaged in this study as subjects. In this study, the QOL scores were evaluated using the SF-8. This is an 8-item version of the SF-36 that yields a comparable 8-dimension health profile and comparable estimates of summary scores for the physical and mental components of health. Results: The QOL score depressed in the patients with JCP compared with healthy subjects (Japanese national norms). Both Mental Component Score (MCS) and Physical Component Score (PCS) scores decreased more in females than in males. In females, MCS were significantly lower than national norms. The older the patients were, the lower PCS scores were showed. The severity of nasal symptoms influenced the PCS scores. Conclusion: These results showed the tendency similar to the early studies using SF-36 questionnaire. The sensitivity of SF-8 in the individual is not better than that of other specific QOL questionnaires, but SF-8 can be answered in a short time compared with other questionnaires including SF-36. We suggested that SF-8 become a useful questionnaire in the future.