高齢者における血清蛋白分画の検討

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  • Study of Serum Protein Fraction in Old People

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Departmental Bulletin Paper

In old people, normal reference range of several clinical chemistry tests change with aging. We studied the difference of the results in serum protein fraction and several clinical chemistry tests between normal adults and old people, and between the healthy old people and bedridden old people. As a result, there was increase of albumin and decrease of globulin in serum protein fraction of the old people compared with that of the normal adults. The results of total protein, cholinesterase, creatinine, and β2-microglobulin in clinical chemistry tests made a significant difference between the old people and the normal adults. The results of creatinephosphokinase, total cholesterol, and zinc sulfate turbidity test made a significant difference between the healthy old people and the bedridden old people. And then, a serum sample having the fraction seemed to be M protein was found serum protein fraction. We analysed it by several electrophoretic analysis, and found that the result was differed from that of other samples.

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