A Patient with Influenza A-associated Encephalopathy Treated with Mild Hypothermic Therapy and Methylprednisolone Pulse Therapy

• George, Imataka

• Hitoshi, Katashio

• Kouji, Wake

• Eiji, Nakagawa

• Hideo, Yamanouchi

• Mitsuoki, Eguchi

Abstract

type:症例報告

type:Case Report

A case of influenza A-associated acute encephalopathy treated with mild hypothermic therapy and methylprednisolone pulse therapy is reported. The patient was a 1 year and 1 month-old girl. Disturbance of consciousness was protracted after fever accompanied by status convulsives, thus she was diagnosed with acute encephalopathy. Influenza A reaction was positive on rapid diagnosis from her nasal mucosa. Hypothermic therapy was initiated in the early stage, and body temperature was kept at 35℃ as rectal and ear drum membrane temperatures for 72 hours. As steroid therapy, 30mg/kg/day methylprednisolone was administered for 3 days. During the course, 7mg/kg amantadine was administered for 5 days. After the combination of therapy, the patient recovered without sequela. No major adverse event occurred during the combined therapy. Still now, there are no established clinical guidelines for this encephalopathy. The combined therapy was effective for influenza A-associated encephalopathy in this patient.

identifier:5

identifier:KJ00004451243

Journal

• Dokkyo journal of medical sciences

  Dokkyo journal of medical sciences 32 (3), 149-152, 2005-10-25

Keywords

• influenza A
• encephalopathy
• hypothermic therapy
• steroid pulse
• methylprednisolone

Details

• CRID: 1050001338513398016
• NII Article ID: 110005519527
• NII Book ID: AA00629581
• ISSN: 03855023
• Web Site: http://id.nii.ac.jp/1199/00000385/
• Web Site: https://search.jamas.or.jp/link/ui/2006206184
• Text Lang: en
• Article Type: journal article
• Data Source:
  • IRDB
  • CiNii Articles
  • KAKEN