Hypertrophic Osteopathy Associated with Disseminated Metastases of Renal Cell Carcinoma in the Dog: A Case Report

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  • CHIANG Yu-Ching
    Department of Veterinary Medicine, College of Bio-Resource and Agriculture, National Taiwan University Veterinary Teaching Hospital, National Taiwan University
  • LIU Chen-Hsuan
    Department of Veterinary Medicine, College of Bio-Resource and Agriculture, National Taiwan University Veterinary Teaching Hospital, National Taiwan University
  • HO Sheng-Yu
    Department of Veterinary Medicine, College of Bio-Resource and Agriculture, National Taiwan University
  • LIN Chung-Tien
    Department of Veterinary Medicine, College of Bio-Resource and Agriculture, National Taiwan University Veterinary Teaching Hospital, National Taiwan University
  • YEH Lih-Seng
    Department of Veterinary Medicine, College of Bio-Resource and Agriculture, National Taiwan University Veterinary Teaching Hospital, National Taiwan University

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A 6-year-old, mixed breed, intact male dog showed signs of left carpal joint swelling and weakness of the forelimbs one month before presentation. The symptoms gradually progressed to bilateral carpal and tarsal joint swelling and tetraparalysis. There were a number of radiographically identified lytic-proliferative bone lesions noted on the axial skeleton. Hypertrophic osteopathy of the metacarpi and all distal long bones was also evident. Because of the deteriorating quality of life and guarded prognosis, the patient was euthanized and a complete necropsy was performed. Renal cell carcinoma, with metastasis to the lung, thoracic vertebrae, ribs, and the right adrenal gland, was diagnosed. To our knowledge, renal cell carcinoma with bone metastases and hypertrophic osteopathy has not been reported in dogs.<br>

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