SF-8とJRQLQの相関 : スギ花粉症を対象に  [in Japanese] CORRELATION BETWEEN THE SF-8 HEALTH STATUS QUESTIONNAIRE AND JRQLQ PATIENTS WITH JAPANESE CEDAR POLLINOSIS  [in Japanese]

【背景】昨今,花粉症治療において,健康関連QOLが重要なアウトカムとされている.現在わが国においては,疾患特異的な調査票であるJFQLQ,または疾患非特異的な調査票であるSF-36が主に用いられている.【目的】疾患特異的な調査票と疾患非特異的な調査票の相関関係や相違を検討することで,花粉症患者におけるより有益なQOL調査を目的とした.【方法】2005年のスギ花粉飛散ピーク時に,大阪府・兵庫県に診療所においてスギ花粉症で受診した患者に,JRQLQおよびSF-8によるQOLを含むアンケート調査を行い,有効回答が得られた患者の症状およびQOLを検討した.【結果】SF-8とJRQLQの因子分析の結果,JRQLQの「睡眠」の項目がSF-8と同じ因子に分類されたが,その他の因子は両方の質問紙からの項目を含んでいなかった.SF-8とJRQLQの間では,特にSF-8の日常役割機能(精神)とJRQLQの「日常生活」「精神生活」で高い相関が見られた.症状スコアとSF-8の間にはほとんど相関が見られない一方,JRQLQの「日常生活」においては,どの症状とも有意な相関が認められた.【結語】SF-8とJRQLQはQOLの異なる側面を測定しており,2つの質問紙を同時に用いることによって,より有益なQOL調査を行うことができると示唆された.

Background: It is reported that the health-related quality of life(HRQL) is an important outcome in the Japanese Cedar Pollinosis(JCP) treatment. In Japan, the disease-specific Japan Rhino-conjunctivitis Quality of Life Questionnaire(JRQLQ) and the generic SF-36 Health Survey(SF-36) has been used. The aim of this study is to investigate more profitable QOL by using both the disease-specific questionnaire and the non disease-specific questionnaire toghther. Method: 411 patients with JCP who visited 10 ENT clinics in Osaka from March 14 to March 26(peak pollen season) in 2005 were questioned, and 240 patients were engaged in this study as subjects. In this study, the QOL scores were evaluated using the JRQLQ and SF-8 Health Survey(Japanese Version), a new, even shorter generic health survey. Results: Using factor analysis and the correlation matrix, we showed that the disease-specific and the general health instrument covered a different half the total measureble HRQL. There was some correlation between the SF-8 items with the JRQLQ domains. There was little correlation between the SF-8 items and symptom scores, while, there was high correlation between the JRQLQ and symptom scores. The "Usual daily activities" domain in the JRQLQ correlated with any rhinoconjunctivitis symptoms. Conclusion: Both JRQLQ and SF-8 can be used to assess the quality of life of patiensts with JCP. Each instrument measures the aspects of the HRQL that hardly overlaps. For an assessment of the HRQL in JCP that is complete and responsive both instruments should be employed together.