マダニ類Ornithodoros moubataのヘモサイトにおけるPDGF-AB,TGF-β,およびそれらのリセプターに関する免疫組織化学的観察

DOI 日本農学文献記事索引 Web Site Web Site 被引用文献1件 参考文献40件
  • MATSUO Tomohide
    Division of Tropical Diseases and Parasitology, Department of Infectious Diseases, Kyorin University School of Medicine
  • CERRUTO NOYA Claudia A.
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine
  • TAYLOR DeMar
    Graduate School of Life and Environmental Sciences, University of Tsukuba
  • FUJISAKI Kozo
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine

書誌事項

タイトル別名
  • Immunohistochemical Examination of PDGF-AB, TGF-.BETA. and their Receptors in the Hemocytes of a Tick, Ornithodoros moubata (Acari: Argasidae)
  • Parasitology: Immunohistochermical examination of PDGF-AB, TGF-β and their receptors in the hemocytes of a tick, Ornithodoros moubata (Acari: Argasidae)
  • Parasitology Immunohistochermical examination of PDGF AB TGF v and their receptors in the hemocytes of a tick Ornithodoros moubata Acari Argasidae
  • Immunohistochemical examination of PDGF-AB, TGF-beta and their receptors in the hemocytes of a tick, <italic>Ornithodoros moubata</italic> (Acari: Argasidae).

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抄録

Growth factors, Platelet Derived Growth Factor (PDGF) and Transforming Growth Factor (TGF)-β, were demonstrated in vertebrate and invertebrate immmunocytes. It is generally known that the growth factors are important in various biological processes, such as the regulation of cell differentiation, development and wound healing. In the present study, the presence of TGF-β1 and PDGF-receptor-α in plasmatocytes and PDGF-AB in granulocytes of a soft tick, Ornithodoros moubata, was confirmed immunohistochemically. The tick midgut might be damaged by intracellular digestion and penetration of protozoa. Therefore, it is considered that PDGF from granulocytes may affect the PDGF-receptor-α in plasmatocytes and TGF-β from plasmatocytes may function to repair the midgut. The results obtained here add to the elucidation of the functions of tick hemocytes.<br>

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