若年者に発症した非Ｂ非Ｃ型肝細胞癌の１例

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  • A Case of non-B, non-C, juvenile Hepatocellular Carcinoma

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A 20-year-old man with non-B non-C hepatitis referred for severe upper abdominal pain underwent. A transarterial chemoembolization for a ruptured liver tumor. Abdominal computed tomography (CT), magnetic resonance imaging (MRI), and angiography showed tumors 7cm in diameter in segment 7/8, 6cm in segement 6, and 1cm in segment 4.Serum AFP was 25, 100ng/ml. An extended right hepatic lobectomy showed stage IVa (T4N0M0). Histological examination of the resected tumor showed moderately differentiated hepatocellular carcinoma (HCC). He is doing well without recurrence 30 months after surgery. Juvenile HCC is relatively rare, and the most common background factor in it in Japan is continuous infection with the hepatitis B virus. This rare case of juvenile HCC had no serum hepatitis virus markers. Such a tumor should be completely resected immediately while liver function is comparatively good, even in advanced juvenile HCC.

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