生体組織の機械的変形が組織内水分子の拡散に与える効果
書誌事項
- タイトル別名
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- Changes in Diffusion Properties of Biological Tissues Associated with Mechanical Strain
- セイタイ ソシキ ノ キカイテキ ヘンケイ ガ ソシキナイ ミズブンシ ノ カクサン ニ アタエル コウカ
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Mechanical strain in biological tissues causes a change in the diffusion properties of water molecules. This paper proposes a method of estimating mechanical strain in biological tissues using diffusion magnetic resonance imaging (MRI). Measurements were carried out on uncompressed and compressed chicken skeletal muscles. A theoretical model of the diffusion of water molecules in muscle fibers was derived based on Tanner’s equation. Diameter of the muscle fibers was estimated by fitting the model equation to the measured signals. Changes in the mean diffusivity (MD), the fractional anisotropy (FA), and diameter of the muscle fiber did not have any statistical significance. The intracellular diffusion coefficient (Dint) was changed by mechanical strain (p<.05). This method has potential applications in the quantitative evaluation of strain in biological tissues, a though it poses several technical challenges.
収録刊行物
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- 日本応用磁気学会誌
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日本応用磁気学会誌 31 (3), 283-287, 2007
公益社団法人 日本磁気学会
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詳細情報 詳細情報について
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- CRID
- 1390282680069397120
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- NII論文ID
- 110006277491
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- NII書誌ID
- AN0031390X
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- ISSN
- 18804004
- 02850192
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- NDL書誌ID
- 8807888
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- NDL-Digital
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可