SYNTHESIS OF BREDININ 5'-ALKYLPHOSPHATES INVOLVING PHOTOCHEMICAL MANIPULATION OF THE IMIDAZOLE MOIETY, AND THEIR ANTITUMOR ACTIVITIES(Communications to the Editor)

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Author(s)

Abstract

Bredinin 5'-oleyl and 5'-cetyl phosphates (2a and 2b), prepared from 1-β-D-ribofuranosyl-5-aminoimidazole-4-carboxamide via a photochemical ring-opening reaction of the imidazole moiety, showed remarkable antitumor effects against various transplantable mouse tumors, and were clearly superior to bredinin (1).

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Codes

  • NII Article ID (NAID)
    110006281447
  • NII NACSIS-CAT ID (NCID)
    AA00602100
  • Text Lang
    ENG
  • ISSN
    00092363
  • Data Source
    NII-ELS 
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