Quantitative Gated Single-Photon Emission Computed Tomography With 99mTc Sestamibi Predicts Major Cardiac Events in Elderly Patients With Known or Suspected Coronary Artery Disease The QGS-Prognostic Value in the Elderly (Q-PROVE) Study
-
- Nagao Tadashi
- Department of Cardiology, Tokyo Medical University
-
- Chikamori Taishiro
- Department of Cardiology, Tokyo Medical University
-
- Hida Satoshi
- Department of Cardiology, Tokyo Medical University
-
- Igarashi Yuko
- Department of Cardiology, Tokyo Medical University
-
- Kuwabara Yoichi
- Department of Cardiovascular Medicine, Graduate School of Medicine, Chiba University
-
- Nishimura Shigeyuki
- Department of Cardiology, Saitama Medical University
-
- Yamazaki Junichi
- Department of Cardiology, Toho University Omori Medical Center
-
- Yamashina Akira
- Department of Cardiology, Tokyo Medical University
書誌事項
- タイトル別名
-
- The QGS-Prognostic Value in the Elderly (Q-PROVE) Study
この論文をさがす
抄録
Background Although electrocardiogram-gated single-photon emission computed tomography (SPECT) may be useful in risk stratification of elderly patients with coronary artery disease (CAD), few studies have prospectively evaluated its prognostic value in this patient population. Methods and Results A total of 175 patients aged 75 years or more with known or suspected CAD were prospectively evaluated by stress gated SPECT using a 20-segment model and an automatic functional analysis. Patients with acute coronary syndrome within the previous 3 months, and those who underwent coronary revascularization within 3 months after the SPECT study were excluded. Outcome assessment included prespecified cardiac events and noncardiac deaths. During a mean follow-up of 3.4 years, there were 18 cardiac events: 2 cardiac deaths, 1 nonfatal myocardial infarction, 3 coronary artery bypass grafting, 5 percutaneous coronary interventions, 1 unstable angina, 4 heart failures, and 2 malignant arrhythmias. Kaplan-Meier survival estimation indicated an event-free survival rate of 98.1% at 3 years in patients without myocardial ischemia, but 79.9% in those with ischemia as documented by gated SPECT (p=0.0001). Multivariate analysis using the Cox proportional hazard model demonstrated that stress-induced myocardial ischemia was the only independent predictor for subsequent cardiac events (p<0.01). Conclusions Stress gated SPECT predicts cardiac events in patients aged 75 years or more with known or suspected CAD and may have a role in risk stratification of this patient population. (Circ J 2007; 71: 1029 - 1034)<br>
収録刊行物
-
- Circulation Journal
-
Circulation Journal 71 (7), 1029-1034, 2007
一般社団法人 日本循環器学会
- Tweet
キーワード
詳細情報
-
- CRID
- 1390282680081928320
-
- NII論文ID
- 110006318400
-
- NII書誌ID
- AA11591968
-
- ISSN
- 13474820
- 13469843
- http://id.crossref.org/issn/13469843
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- Crossref
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可